San Francisco by more than 8.5 trades near even money, and the volume tells you that number is the fight. Arizona lost cornerback Will Johnson to injured reserve with a neck injury and had Max Melton and Garrett Williams banged up, thinning a secondary that has to hold up against Brock Purdy, who opened the season completing better than 80% of his throws. The counterweight is San Francisco's own attrition, nine players to IR since cutdown, Nick Bosa nursing a calf, Mike Evans a hip. A healthy Purdy against a depleted Arizona back end argues over the number, a short-handed pass rush argues under it.
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